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Malvaceae

Hibiscus sabdariffa

Roselle · Hibiscus · Karkade · Sorrel

Trial support Caution
Part used
flowerfruit
Native range
West Africa; cultivated across the tropics
Morphology
An annual shrub to two and a half metres with lobed leaves and pale yellow flowers, whose fleshy deep-red calyces swell after flowering and are the part harvested.

What is in it

anthocyanins delphinidin-3-sambubioside
organic acids hibiscus acid, citric acid
polyphenols

Evidence

Among the better-supported entries. Multiple randomised trials and meta-analyses show a modest but consistent reduction in systolic and diastolic blood pressure, with effect sizes smaller than antihypertensive drugs and comparable to some dietary interventions.

Safety

A food and generally well tolerated. Because the blood pressure effect is real, it is additive with antihypertensive treatment. Reduces levels of some drugs. Traditionally avoided in pregnancy.

Interactions: Additive with antihypertensives; Reduces plasma levels of hydrochlorothiazide and of chloroquine

Regulatory: Permitted as a food and as a listed medicine ingredient.

Historical use

Drunk as a cold or hot infusion across west and north Africa, Egypt, the Caribbean and Mexico — karkade, bissap, agua de Jamaica. Used for blood pressure and as a cooling drink.

Recorded as history and attributed where possible. Long use establishes that a plant was widely used, not that it worked, and not that it was safe.

Worth knowing

Roselle is one of the few plants in this collection where a large body of ordinary daily use and a respectable trial literature agree, and the finding is modest and useful rather than dramatic.

It also demonstrates the point that a real effect creates a real interaction. Because hibiscus genuinely lowers blood pressure, someone already on antihypertensive medication who starts drinking it daily is adding to their treatment without anyone recording it — and it separately reduces blood levels of hydrochlorothiazide, a common antihypertensive, which pushes in the other direction.

An inert tea cannot do either of those things. This is what it looks like when a herb works.

Nomenclature verified against GBIF backbone taxonomy.